Life Sciences

Real-world evidence in the cloud

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SHARE: Real-World Evidence in the Cloud: How Technology is Revealing the Big Picture in Pharma 2 T he collection and analysis of data generated outside of restricted clinical trials are now cr it ic a l to phar ma comp anies. Data gathered in the routine deliver y of healthcare can be mined to uncover insights into treatment efficacies and outcomes in the real world. Such insights, known as real-world evidence (RWE), benefits teams working across the drug lifecycle by showing how larger, heterogeneous patient populations interact with the healthcare system and respond to medicines. Until recently, pharma companies and other healthcare stakeholders had access to a limited range of real- world data. Outside of formalized clinical trials, companies were only able to collect basic observational research data by monitoring billing codes submitted to healthcare payers, or from registry studies, giving them a limited picture of how their products were used in practice and their effect on patients. These data sources are now just a few parts of a much broader tapestry. Today, companies can pull in longitudinal patient information from electronic medical records (EMRs), genomic studies, social media, wearables and other sources of real-world data to build a more detailed, robust understanding of the use and value of their products. RWE is now a key resource for every step in the life cycle from drug discovery to commercialization. This new normal grew out of the simultaneous expansion of the breadth and depth of datasets, growing focus on value—in some cases by tying payments to outcomes—and need to make processes across the drug lifecycle faster and more efficient. The AWS Cloud is facilitating RWE by making it easier for pharma companies to ingest vast datasets from a range of sources, and by providing analytical tools, including artificial intelligence capabilities, to

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