Life Sciences

Real-world evidence in the cloud

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SHARE: Real-World Evidence in the Cloud: How Technology is Revealing the Big Picture in Pharma 5 that is deployable in minutes from AWS ser vice catalog, makes it possible to create secure, easily searchable data lakes in minutes, as opposed to the potentially long lead times to procure and set up on-premises IT infrastructure. The company-wide data access enabled by cloud- based data lakes is the first step to empowering teams to seize opportunities created by RWE. The second step is to enable workers of all levels of technical know-how to glean insights from data. Collating and mining real-world data for evidence was traditionally a technically demanding task. This is changing, though. Celgene has created self-ser vice, point-and-click applications to enable non-coding staff to perform analyses. 1 With the associated powerful data analytics in the cloud, Celgene reduced patient cohort analysis time from months to minutes. Using these applications, anyone can question data and produce interactive visualizations, cutting the time and resources it takes to generate insights. The flexibility afforded by building a data lake on AWS means you can ingest data in any format and can perform data analysis on-demand, regardless of what new types of data may be available from pharma patients in the future. And hosted in the highly secure cloud infrastructure with programs to help organizations meet local and regional regulatory rules for data protection and provisioning, including HIPAA, HITRUST, and GDPR requirements. A 2017 Deloitte survey 2 suggests companies that realize these benefits by adopting cloud systems are happier 1 Invent 2017: Real World Evidence Platforms to Enable Therapeutic Innovation (LFS302). (2017). http://paperpile.com/b/xoZLH3/4WNp 2 Getting real with real-world evidence. Available at: https://www2.deloitte. com/content/dam/Deloitte/us/Documents/life-sciences-health-care/us-ls- 2017-real-world-evidence-survey-031617.pdf. (Accessed: 26th June 2018) with their RWE setups than peers that use on-premises infrastructure. e survey found more than half of leading pharma companies are investing to significantly improve RWE capabilities, typically due to dissatisfaction with their existing on-premises systems. In contrast, companies with cloud-based RWE systems are far less likely to feel the need to significantly improve their capabilities, with 80% stating they are content with their RWE capabilities. This satisfaction gap reflects the fact that the scalability, security, and speed of the cloud make it a better fit for the RWE needs of modern pharma companies. HARNESSING ARTIFICIAL INTELLIGENCE TO ACCELERATE ANALYSIS Easy-to-use, real-world data analysis tools are being supercharged by artificial intelligence and machine learning. Today, vast quantities of data are available but the size of the repositories and complexity of the information makes manual, human-powered analysis impractical, if not impossible. Fortunately, artificial intelligence and machine learning can sift through data far quicker than manual inspection, making it possible to generate insights within a fraction of the time it would take a human. At the same time, AWS is lowering the barriers to entry to machine learning to expand what companies can learn from their data. 3 GE Healthcare is using services such as Amazon SageMaker to streamline the development and deployment of machine learning models to help radiologists improve health outcomes while reducing errors. S i m i l a r l y, a p h a r m a c o m p a ny c o u l d m i n e reimbursement claims data, historic study site 3 Partnering for AI Innovation. WSJ (2018). Available at: https://partners. wsj.com/aws/partnering-for-ai-innovation. (Accessed: 24th July 2018)

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