Life Sciences

Whitepaper: Improving the diagnosis of infectious diseases with microbial genomic analysis

Issue link: https://read.uberflip.com/i/1331299

Contents of this Issue

Navigation

Page 2 of 2

3 1. Blauwkamp T., et al. Nat. Microbiol. 2019;4(4):663-674. https://www.ncbi.nlm.nih.gov/pubmed/30742071 A GENOMEWEB / AWS WHITE PAPER JANUARY 2020 Next, a relative abundance is calculated for each microbial taxon detected in the sample. The third VWHSLVWRƓOWHURXWDQ\SRWHQWLDOIDOVHSRVLWLYHV VXFKDVLGHQWLƓFDWLRQRIPLFURELDOFHOOIUHH'1$ that originated from the environment. ŏ7KH ZD\ WKH ƓOWHU ZRUNV LV E\ XVLQJ WKH VHW of control samples that are processed and sequenced within each batch," explained Dr. Bercovici. "A probabilistic approach is trained on these control samples, per batch, and that DOORZVXVWRƓOWHUZKDWDSSHDUVWREHEDFNJURXQG noise." A key point is that the contamination SURƓOHFKDQJHVRYHUWLPHŏ

Articles in this issue

Links on this page

view archives of Life Sciences - Whitepaper: Improving the diagnosis of infectious diseases with microbial genomic analysis