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Transforming manufacturing in Life Sciences One Pager

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Transforming manufacturing in Life Sciences Manufacturing can and should be a competitive advantage." Boston Business Journal, 2019 Unlocking value Complexities of the digital supply chain Smart manufacturing: Agile, reliable, secure Global Product 1 Product 2 … !"#$ %&'()*'* Amazon EC2 Amazon SageMaker AWS RDS Amazon QuickSight AWS Kinesis Raw material, CDMO Schedule, demand IoT and data management Suppliers Drug substance/API Drug product Packaging Distribution/ logistics QUALITY VISIBILITY Manufacturing Distribution The signal is used to manage downstream activities Customer and patient provides demand signal • Access critical plant information at any time • Measure and improve OEE • Compare KPIs and metrics across the enterprise • Benchmark machines, lines, and plants • Measure quality performance • Improve worker safety • Discover new services opportunities PRODUCTION • Automate data capture • Drive continuous process improvement • Predict out-of-control processes and failures • Monitor regulatory info—track and trace, genealogy • Increase equipment and capacity utilization • Reduce maintenance costs • Increase NPI time • Provide continuous process verification • Determine root cause • Reduce scrap and defects • Increase yield • Control processes with stricter tolerances • Set up alerts to maintain process control • Monitor equipment health • Enable business process automation In the factory, this is used to plan the production run Supplier Sales Supplier network Raw materials inventory Production phases Shipped out Finished good stocks Transit stocks Last mile fulfillment Paul Hudson, CEO, Sanofi Today's supply chain needs to be connected. Starting with the patient and working backwards, a connected supply chain generates demand signals that manage the supply (manufacturing process) and creates a tightly-knit "sense-and-respond" supply chain. Amazon Web Services (AWS) can help you transform your traditional, independent, and fragmented sites into an integrated organization for the future state of smart manufacturing.

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