Life Sciences

AWS Digital Therapeutics Reference Architecture

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For more information on Pharma and Biotech or other ways AWS can help your organization visit us at: aws.amazon.com/health/biotech-pharma © 2020, Amazon Web Services, Inc. or its Affiliates. All rights reserved. Data Sources Patients can use personal wearables, connected with a custom mobile (lifestyle or a companion mobile) application to transfer data events. Other smart sensors can optionally be connected to the mobile application. Clinical Applications Data can be ingested through various clinical applications like Electronic Medical Records, health information exchanges, and customer commercial applications. Real-time Data Ingestion The mobile application sends data and events to Amazon Pinpoint, authenticating through Amazon Cognito. Batch Data Ingestion Data replication from relational database sources is performed through AWS Database Migration Service. AWS Batch is used to consume data from public/private APIs. AWS DataSync is used to automate data movement from on-premises storage to Amazon Simple Storage Service (Amazon S3). AWS Glue is used for managed ETL and process the incoming data. Data Preparation AWS Lake Formation is used to set up a centralized, curated, and secure repository in days, for storing raw and curated data. Storage and Archival Amazon S3 acts as the central storage layer and leverages life cycle policies to move data to Amazon S3 Glacier for archival purposes, saving costs. Data Analytics and Visualization Amazon Redshift is used as a data warehouse to store curated data. Semi-structured and unstructured data can be processed by Amazon EMR and Amazon Athena is used for ad-hoc querying. Amazon SageMaker is used to build custom ML driven predictive models to drive effective outcomes. Amazon Quicksight provides a rich visualization layer. Event Driven Tasks and Alerts Amazon DynamoDB and AWS Lambda are used for hosting a rules engine to drive effective outcomes. Custom machine learning models can be used to automatically create rules which can be reviewed by a team of care coordinators. Amazon Pinpoint is used to deliver on demand messages to patients through email, SMS, push notifications, and voice technology. Digital therapeutics and precision medicine AWS reference architecture 1 1 2 2 3 3 8 8 5 5 7 7 6 6 4 4

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