Research paper

Internet-delivered cognitive behavioural therapy for depression and anxiety in breast cancer survivors: Results from a randomised controlled trial

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Received: 17 August 2022 - Revised: 3 January 2023 - Accepted: 5 January 2023 DOI: 10.1002/pon.6097 O R I G I N A L A R T I C L E Internet‐delivered cognitive behavioural therapy for depression and anxiety in breast cancer survivors: Results from a randomised controlled trial Selin Akkol‐Solakoglu 1 | David Hevey 2 1 SilverCloud Science, SilverCloud Health Ltd, Dublin, Ireland 2 School of Psychology, Trinity College Dublin, Dublin, Ireland Correspondence Selin Akkol‐Solakoglu, SilverCloud Science, SilverCloud Health Ltd, Dublin, Ireland. Email: akkolsos@tcd.ie Funding information Trinity College Dublin [Correction added on 08 May 2023, after first online publication: In the Results section of the abstract, "…Hedge's g = −0.094…" has been corrected to "…Hedge's g = −0.94…" in this version.] Abstract Objective: Depression and anxiety symptoms are common among breast cancer survivors. Access to evidence‐based psychological therapy remains a major chal- lenge. Despite the proven effectiveness of internet‐delivered cognitive behavioural therapy (iCBT) in reducing depression and anxiety, the research with cancer sur- vivors is still limited. This study evaluated the effectiveness of an iCBT intervention on depression and anxiety, quality of life, fear of recurrence, active and avoidant coping, and perceived social support in breast cancer survivors. Methods: Seventy‐two participants were randomised to a 7‐module guided iCBT intervention or treatment‐as‐usual (TAU). Depression and anxiety symptoms were measured using the Hospital Anxiety and Depression Scale total score (HADS‐T). The secondary measures included the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC‐QLQ), Breast Cancer Worry Scale (CWC), Brief Coping Orientation to Problems Encountered (Brief COPE), Medical Outcomes Study Social Support Survey (MOS‐SSS). All were completed at baseline, post‐intervention, and 2‐month follow‐up. Groups were compared using linear mixed models. Results: Although non‐significant, iCBT group had lower HADS‐T scores than TAU at post‐intervention. This difference was statistically significant at 2‐month follow‐ up (Hedge's g = −0.94). No significant group‐by‐time interaction effects were found for quality of life, fear of recurrence, active coping, avoidant coping, and perceived social support. The intervention adherence was acceptable; 52.8% (n = 28) completed all seven modules. Conclusions: iCBT intervention demonstrated its preliminary effectiveness in reducing distress in breast cancer survivors. K E Y W O R D S anxiety, breast cancer, cognitive behavioural therapy, depression, internet‐delivered, psycho‐ oncology This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, pro- vided the original work is properly cited. © 2023 The Authors. Psycho-Oncology published by John Wiley & Sons Ltd. 446 - Psycho‐Oncology. 2023;32:446 – 456. wileyonlinelibrary.com/journal/pon

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