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Powering Discovery with JAX iPSC Models

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OP0285 2026.05 micetech@jax.org 1.800.422.6423 (US) 1.207.288.5845 (International) VIEW iPSC CATALOG EXPLORE iPSC RESOURCES Genetically Engineered Isogenic iPSC Lines Donor-Derived Disease-Specific iPSC Lines Controls Isogenic controls comprising unedited parental and mutation-corrected lines within a uniform genetic background Healthy cohort–derived iPSCs, mutation- corrected lines, and unaffected familial comparators Primary Use Cases Designed for controlled, hypothesis- driven studies • Mechanistic and functional genomics studies • Target, pathway, and allelic dosage validation • Assay development and comparative screening Designed to capture real-world biological diversity • Population-scale disease modeling • Patient stratification and variability analysis • Precision medicine–focused research

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