3.2 | Time-to-event analysis
In total, after accounting for censored data points, 29.2% (n = 26) of
cases were classified as relapse events within the 9-month period.
Therefore, 70.8% (n = 63) remained in remission at 9 months post-
treatment. Of those who relapsed, 53.8% (n = 14) experienced a
relapse of depression and anxiety; 7.7% (n = 2) experienced a relapse
of depression only; and 38.4% (n = 10) experienced a relapse of
T A B L E 1 PHQ-9 and GAD-7 scores
for all participants in the intervention
arm, and a breakdown of the scores for
the ineligible and eligible subgroups
Baseline End-of-treatment 3 months 6 months 9 months
Intervention-arm, n 241 186 182 177 173
PHQ-9 mean (SD) 14.4 (4.9) 8.2 (5.7) 7.2 (5.8) 6.8 (5.7) 6.8 (5.5)
GAD-7 mean (SD) 12.7 (4.7) 7.4 (4.7) 6.9 (5.3) 6.5 (5.5) 6.1 (4.8)
Ineligible, n 152 97 96 93 93
PHQ-9 mean (SD) 15.2 (5.0) 11.9 (5.1) 9.2 (6.1) 8.9 (5.6) 8.8 (5.7)
GAD-7 mean (SD) 13.3 (4.7) 11.2 (4.4) 9.1 (5.9) 8.5 (5.0) 7.4 (4.9)
Eligible, n 89 89 86 84 80
PHQ9 mean (SD) 13.0(4.5) 4.0 (2.6) 4.9 (4.6) 4.6 (4.9) 4.5 (4.3)
GAD7 mean (SD) 11.5 (4.5) 3.2 (2.2) 4.5 (3.9) 4.2 (4.3) 4.5 (4.3)
T A B L E 2 Descriptive statistics for included participants at 3 months (end-of-treatment)
Remission (n = 63) n (%) Relapse (n = 26) n (%) Total (n = 89) n (%) Χ
2
df p
Age M (SD) 37.02 (13.79) 29.54 (10.88) 34.83 (13.39) 2.464
d
87 0.016
Gender
Male 17 (27) 3 (11.5) 20 (22.5) 2.520 1 0.112
Female 46 (73) 23 (88.5) 69 (77.5)
Ethnicity
a
White 53 (85.5) 19 (73.1) 72 (81.8) 1.896 1 0.169
Other 9 (14.5) 7 (26.9) 16 (18.2)
Long-term condition
Yes 10 (15.9) 6 (24) 16 (18.2) 0.795 1 0.373
No 53 (84.1) 19 (76) 72 (81.8)
Employment status
b
Employed 47 (79.7) 18 (69.2) 65 (76.5) 1.091 1 0.296
Unemployed/student 12 (20.3) 8 (30.8) 20 (23.5)
Medication
c
Taking 16 (27.6) 7 (26.9) 23 (27.4) 0.004 1 0.950
Not taking 42 (72.4) 19 (73.1) 61 (72.6)
MINI diagnosis
a
Yes 15 (24.2) 7 (26.9) 22 (25) 0.073 1 0.787
No 47 (75.8) 19 (73.1) 66 (75)
PHQ-9 residual symptoms
e
Yes 24 (38.1) 13 (50) 37 (41.6) 1.074 1 0.300
No 39 (61.9) 13 (50) 52 (58.4)
GAD-7 residual symptoms
Yes 20 (31.7) 10 (38.5) 30 (33.7) 0.371 1 0.542
No 43 (68.3) 16 (61.5) 59 (66.3)
a
Total n = 88.
b
Total n = 85.
c
Total n = 84.
d
T test value.
e
Residual symptoms = PHQ-9 score 5–9; GAD-7 score 5–7.
1772 PALACIOS ET AL.
